Bioinspired and biocompatible chemistry
Nature and biological systems account for inspiration and models for the development of new smart functional compounds and materials for medicinal applications (biomaterials, biocatalysts, medicinal applications). Moreover, the study of biomolecules is the clue to understand the molecular basis of biological processes (biomolecules, and metabolomics).
Research topics
Advanced synthetic methodologies for rationally designed small-molecule targeted anti-cancer drugs
Applications of coordination chemistry in pre-clinical studies (oncology and nuclear medicine): from the design of new chelators and targeting molecules to the formation of metal complexes.
Coordination compounds of transition metal complexes with oligodentate Schiff base ligands for their application as anticancer, antibacterial and antifungal agents
Design and synthesis of coordination compounds of transition metals as chiral probes and water-splitting catalysts
Hybrid ceramic-based biomaterials for therapeutic and environmental applications
Metallo-substituted heme proteins as possible bio-electrocatalysts.
Involvement of native and mutated metalloproteins in redox catalysis and oxidative stress.
· Synthesis of mesoporous (bio)ceramic scaffolds and functionalization with biomolecules and nanoparticles to add orthogonal therapeutic or biocidal properties
· Metabolomics on tissues, cells and biofluids via Nuclear Magnetic Resonance (NMR)
Researchers: Gianantonio Battistuzzi, Marco Borsari, Erika Ferrari, Gigliola Lusvardi, Gianluca Malavasi, Adele Mucci, Luca Rigamonti
